<?xml version="1.0" encoding="utf-8"?>
<schema xmlns:lavipharm="http://www.lavipharm.com/20251231" xmlns="http://www.w3.org/2001/XMLSchema" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xl="http://www.xbrl.org/2003/XLink" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:ref="http://www.xbrl.org/2006/ref" xmlns:esef_cor="https://www.esma.europa.eu/taxonomy/2024-03-27/esef_cor" xmlns:gen="http://xbrl.org/2008/generic" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2022-03-31" targetNamespace="http://www.lavipharm.com/20251231" elementFormDefault="qualified" xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric" xmlns:num="http://www.xbrl.org/dtr/type/numeric">
  <!-- INTEGIX by Ez-XBRL -->
  <import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"/>
  <import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"/>
  <import namespace="http://xbrl.org/2005/xbrldt" schemaLocation="http://www.xbrl.org/2005/xbrldt-2005.xsd"/>
  <import namespace="https://www.esma.europa.eu/taxonomy/2024-03-27/esef_cor" schemaLocation="https://www.esma.europa.eu/taxonomy/2024-03-27/esef_cor.xsd"/>
  <import namespace="http://www.xbrl.org/dtr/type/2022-03-31" schemaLocation="https://www.xbrl.org/dtr/type/2022-03-31/types.xsd"/>
  <annotation>
    <appinfo>
      <link:roleType roleURI="http://www.lavipharm.com/role/NotesAndMandatoryItems" id="NotesAndMandatoryItems">
        <link:definition>0000 - Statement - Notes And Mandatory Items</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
      </link:roleType>
      <link:roleType roleURI="http://www.lavipharm.com/role/rdiime" id="rdiime">
        <link:definition>0000 - Statement - Κέρδη ή ζημίες</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
      </link:roleType>
      <link:roleType roleURI="http://www.lavipharm.com/role/attaiikonomiki" id="attaiikonomiki">
        <link:definition>0000 - Statement - Κατάσταση οικονομικής θέσης</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
      </link:roleType>
      <link:roleType roleURI="http://www.lavipharm.com/role/attaietavolndonefalaon" id="attaietavolndonefalaon">
        <link:definition>0000 - Statement - Κατάσταση μεταβολών ιδίων κεφαλαίων</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
      </link:roleType>
      <link:roleType roleURI="http://www.lavipharm.com/role/attaiameiaknon" id="attaiameiaknon">
        <link:definition>0000 - Statement - Κατάσταση ταμειακών ροών</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
      </link:roleType>
      <link:roleType roleURI="http://www.lavipharm.com/role/Notes" id="Notes">
        <link:definition>0000 - Disclosure - Notes</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
      </link:roleType>
      <link:roleType roleURI="http://www.lavipharm.com/role/PNLAdditionalCalculations" id="PNLAdditionalCalculations">
        <link:definition>0000 - Statement - PNL additional calculations</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
      </link:roleType>
      <link:roleType roleURI="http://www.lavipharm.com/role/Anchoring" id="Anchoring">
        <link:definition>0001 - Anchoring</link:definition>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:linkbaseRef xlink:type="simple" xlink:href="213800USC69CRPRGWJ15-2025-12-31_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/>
      <link:linkbaseRef xlink:type="simple" xlink:href="213800USC69CRPRGWJ15-2025-12-31_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/>
      <link:linkbaseRef xlink:type="simple" xlink:href="213800USC69CRPRGWJ15-2025-12-31_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/>
      <link:linkbaseRef xlink:type="simple" xlink:href="213800USC69CRPRGWJ15-2025-12-31_lab-en.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/>
      <link:linkbaseRef xlink:type="simple" xlink:href="213800USC69CRPRGWJ15-2025-12-31_ref.xml" xlink:role="http://www.xbrl.org/2003/role/referenceLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/>
      <link:linkbaseRef xlink:type="simple" xlink:href="213800USC69CRPRGWJ15-2025-12-31_lab-el.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/>
      <link:linkbaseRef xlink:type="simple" xlink:href="https://www.esma.europa.eu/taxonomy/2024-03-27/esef_cor-lab-el.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/>
      <link:linkbaseRef xlink:type="simple" xlink:href="https://www.esma.europa.eu/taxonomy/2024-03-27/esef_cor-gen-el.xml" xlink:role="http://www.xbrl.org/2003/role/linkbaseRef" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/>
    </appinfo>
  </annotation>
  <element name="CashAndCashEquivalentsAndRestrictedCashAndCashEquivalents" id="lavipharm_CashAndCashEquivalentsAndRestrictedCashAndCashEquivalents" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit"/>
  <element name="CashAndCashEquivalentsAndRestrictedCashAndCashEquivalentsFromContinuingAndDiscontinuedOperations" id="lavipharm_CashAndCashEquivalentsAndRestrictedCashAndCashEquivalentsFromContinuingAndDiscontinuedOperations" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit"/>
  <element name="CashAndCashEquivalentsAndRestrictedCashAndCashEquivalentsFromDiscontinuedOperations" id="lavipharm_CashAndCashEquivalentsAndRestrictedCashAndCashEquivalentsFromDiscontinuedOperations" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit"/>
  <element name="CashAndCashEquivalentsAndRestrictedCashAndCashEquivalentsIfDifferentFromTheStatementOfFinancialPosition" id="lavipharm_CashAndCashEquivalentsAndRestrictedCashAndCashEquivalentsIfDifferentFromTheStatementOfFinancialPosition" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit"/>
  <element name="DisclosureOfDistributionExpenses" id="lavipharm_DisclosureOfDistributionExpenses" type="dtr-types:textBlockItemType" abstract="false" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true"/>
  <element name="GainLossFromDerecognitionOfSubsidiaries" id="lavipharm_GainLossFromDerecognitionOfSubsidiaries" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit"/>
  <element name="OtherTransactionsBetweenEquity" id="lavipharm_OtherTransactionsBetweenEquity" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit"/>
  <element name="PaymentsTowardsBorrowingsClassifiedAsFinancingActivitiesGreekState" id="lavipharm_PaymentsTowardsBorrowingsClassifiedAsFinancingActivitiesGreekState" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit"/>
  <element name="ProceedsFromBorrowingsClassifiedAsFinancingActivitiesGreekState" id="lavipharm_ProceedsFromBorrowingsClassifiedAsFinancingActivitiesGreekState" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit"/>
  <element name="ProceedsFromSaleAndLeasebackOfTangibleAssets" id="lavipharm_ProceedsFromSaleAndLeasebackOfTangibleAssets" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="debit"/>
  <element name="ProfitLossBeforeTaxContinuingOperations" id="lavipharm_ProfitLossBeforeTaxContinuingOperations" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit"/>
  <element name="ValuationGreekGovernmentBonds" id="lavipharm_ValuationGreekGovernmentBonds" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" xbrli:balance="credit"/>
</schema>