As of September 30, 2003, the shares of the Company PERSEUS S.A. are traded on the ATHEX ex-rights, in terms of 1 new common registered (CR) share for every 5 old common registered (CR) shares held, at an issue price of 2.50 EURO per share. The trading rights period is set from 6.10.2003 until 15.10.2003 and the subscription rights period is set from 6.10.2003 until 21.10.2003.

According to Regulation 24/273/10.6.2003 of the Board of Directors of the Capital Market Commission and the Regulation No 45 of the ATHEX Board of Directors, the trading limits of the share price only for the trading session of the ATHEX on September 30, 2003, are set as follows:

Adjusted price: 4.60 euro

Closing price of the last day of trading (29/9/2003): 5.02 euro

Limit up +12%: 5.62 euro

Limit up +18%: 5.92 euro

Limit down -12%: 4.04 euro

Limit down -18%: 3.78 euro

According to the above and taking into account that in the OASIS subsystem as start price is considered the adjusted share price, the upper and lower trading limits are set as follows:

Start price: 4.60 euro

Limit up Α΄ + 22.17%: 5.62 euro

Limit up Β΄ + 28.70%: 5.92 euro

Limit down Α΄ -12.17%: 4.04 euro

Limit down Β΄ -17.83%: 3.78 euro

Detailed information for the share capital increase through a rights issue is included in the related Prospectus that has been approved by the ATHEX BoD and will be available at the ATHEX, the offices of the issuer, the offices of the consultant and www.ase.gr.