BIOTER S.A.

Announcement pursuant to Law 3556/2007

BIOTER S.A. pursuant to Law 3556/2007 announces that the shareholder Mr.George Mavroskotis General Manager and Managing Director of BIOTER SA, person obligated to notify pursuant to Law 3340/2005, on 03/12/2008 purchased 5,760 BIOTER's common registered shares of total value of Euro 4,556.36 and on 03/13/2008 purchased 3,200 BIOTER's common registered shares of total value of Euro 2,431.14.