BIOTER S.A.

Announcement pursuant to Law 3556/2007

BIOTER S.A. pursuant to Law 3556/2007 announces that the shareholder Mr. Tsapaliras Aristotelis, Bioter's Finance Director and Member of the Board of Directors, person obligated to notify pursuant to Law 3340/2005, on 10/09/2008 purchased 7,000 BIOTER's common registered shares of total value of Euro 2,520.00